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Machine learning diagnostic models for pancreatic ductal adenocarcinoma based on urinary biomarkers exhibit asymmetric cross-sex generalization, where male-trained models transfer effectively to females but female-trained models perform poorly on males. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Asymmetric generalisation and robustness of machine learning architectures in complex biological systems: The case of pancreatic ductal adenocarcinoma

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