The purpose of this study was to develop a method for producing high-resolution mapping populations without the disadvantages of rare alleles and population structure, combining the advantages of biparental and association mapping: Advanced Intercross-Derived Recombinant Inbred Lines (AID-RILs). We used male sterility to create an AID-RIL population in rice. Genome-wide association studies in this population achieved high detection power and low false-positive rate for identifying quantitative-trait nucleotides, with the FarmCPU method showing the best performance. The strategy could be extended to multi-parental crosses
Yang et al. (2026) studied this question.