A single dose of psilocybin may provide rapid relief for people with major depressive disorder (MDD), with benefits emerging within days and lasting for several weeks, according to a randomized clinical trial published May 15 in JAMA Network Open . Researchers of the study, “Short‐Term and Late‐Term Effects of Psilocybin on Symptoms in Major Depression: A Randomized Clinical Trial,” found that patients receiving psilocybin experienced significantly larger reductions in depression scores compared with those given an active placebo, meeting the study's primary endpoint at eight days.
Valerie A. Canady (Fri,) studied this question.