Intramolecular Asymmetric Iodoetherification of ortho-Allylphenols Catalyzed by Chiral Multinuclear Zn Bis(aminoimino)binaphthoxide

Key Points

• The central aim is to achieve asymmetric intramolecular iodoetherification of ortho-allylphenols using a chiral catalyst.
• Catalytic asymmetric intramolecular iodoetherification of ortho-allylphenols using a multinuclear zinc complex
• Subsequent azidation of chiral compound followed by click reaction with phenylacetylene
• Yield assessment of generated dihydrobenzofuran compounds.
• Iodoetherification achieved up to 99% yields with 85% enantiomeric excess (ee)
• Successful generation of triazole-substituted dihydrobenzofuran while preserving chirality