Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 31, 2026Journal of the American Academy of Orthopaedic Surgeons

Safety of Celecoxib in Postoperative Patients With Documented Sulfonamide Allergies

View Full Paper
Ask AI
Bookmark
Share

Authors

JSJosiah SnowdenCGCatharina GaethAPAlex Penner

Discussion

Loading...

Member takes

Overview

Retrospective cohort study evaluates celecoxib safety in postoperative patients with sulfonamide allergies, suggesting safe use for pain management.

Key Points

  • The study aims to evaluate the safety of celecoxib in postoperative orthopaedic patients with documented sulfonamide allergies.
  • Retrospective cohort study conducted at a single tertiary center.
  • Inclusion of orthopaedic surgery patients with sulfonamide allergies who received celecoxib postoperatively, from January 2020 to December 2022.
  • Review of postoperative notes, telephone encounters, and emergency department records for allergic reactions.
  • Sixty-one patients met inclusion criteria with 21.3% presenting for various issues post-surgery.
  • Two patients reported allergic reactions linked to other medications, not celecoxib.
  • One gastrointestinal bleed occurred in a patient also taking aspirin, but no reactions were attributed to celecoxib.

Cite This Study

Snowden et al. (2026) studied this question.

synapsesocial.com/papers/6a1bd12d5783ba022b6fcc9dhttps://doi.org/10.5435/jaaos-d-25-01556
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rising drug allergy alert overrides in electronic health records: an observational retrospective study of a decade of experience2015 · 123 citations
  2. 2Overriding of Drug Safety Alerts in Computerized Physician Order Entry2005 · 1,135 citations
  3. 3Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-21999 · 1,315 citations
  4. 4Sulfonamide cross-reactivity: Is there evidence to support broad cross-allergenicity?2013 · 79 citations
  5. 5Sulfonamide Allergies2019 · 85 citations