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May 31, 2026BMJ OpenOpen Access

SDACS-12 scale predicts postdischarge depression in ACS-PCI patients with an AUC of ~0.80.

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Why the study?

The authors sought to develop a simple screening scale to predict postdischarge depression in patients with ACS after PCI and to verify its reliability, validity, and cutoff value.

Can a simple 12-item screening scale reliably predict postdischarge depression in patients with ACS-PCI?

Population

42 patients with ACS after PCI across two hospitals in Japan

Design

Prospective longitudinal study

Follow-up

3 months after discharge

Key result

The 12-item SDACS-12 screening scale predicted postdischarge depression in ACS-PCI patients with an AUC of 0.799 (95% CI 0.629 to 0.970) at a cutoff of 28 points.

Authors

MDMana DoiYSYuko SakamotoATAsumi Tanaka

Discussion

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Overview

May aid post-ACS-PCI depression screening; leaves open validation in larger prospective cohorts before clinical use.

Key Points

  • The aim is to create a screening scale to predict depression after discharge in patients with acute coronary syndrome post PCI and assess its effectiveness.
  • Conducted a prospective longitudinal study 1 week and 3 months after discharge in two hospitals in Japan.
  • Surveyed 183 patients, with valid responses from 42 patients, yielding a 23.0% response rate.
  • Used item-total correlations and principal component analysis to refine the scale, resulting in 12 items.
  • Cronbach’s alpha coefficient was 0.832, indicating good reliability.
  • Predictive validity demonstrated significant correlations with an area under the curve of 0.799 (95% CI 0.629 to 0.970).
  • Identified a cut-off value of 28 points, with sensitivity of 1.000, specificity of 0.553, and low positive predictive value (0.190).

Study Design

Type

Observational (n=42)

Multicenter

Yes

Structured PICO

Can a simple 12-item screening scale reliably predict postdischarge depression in patients with ACS-PCI?

P
Population
42 patients with acute coronary syndrome after percutaneous coronary intervention (ACS-PCI) in Japan (from 183 potential candidates, 23.0% response rate).
I
Intervention
A 12-item screening scale (SDACS-12) to predict postdischarge depression.
O
Outcome
Reliability, validity, and predictive ability of the screening scale for postdischarge depression.patient reported

Main Result

Effect estimate: AUC 0.799 (95% CI 0.629 to 0.970)

A newly developed 12-item screening scale (SDACS-12) shows high sensitivity but low specificity for predicting postdischarge depression in ACS patients after PCI.

Limitations

  • Moderate variance explained by PCA
  • Low specificity and positive predictive value
  • Low response rate (23.0%)
  • moderate variance explained by PCA
  • low specificity
  • low positive predictive value
  • low response rate (23.0%)

Cite This Study

Doi et al. (2026) conducted an observational in Acute coronary syndrome after percutaneous coronary intervention (n=42). SDACS-12 screening scale was evaluated on Predictive ability for postdischarge depression (Area under the ROC curve) (AUC 0.799, 95% CI 0.629 to 0.970). The 12-item SDACS-12 screening scale predicted postdischarge depression in ACS-PCI patients with an AUC of 0.799 (95% CI 0.629 to 0.970) at a cutoff of 28 points.

synapsesocial.com/papers/6a1bd1745783ba022b6fd0a2https://doi.org/10.1136/bmjopen-2025-099542
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