PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
Synapse
⌘+K
Synapse
May 31, 2026Journal of Preventive Medicine and Public HealthOpen Access

Repeated Health Screening Measures and Incident Ischemic Stroke: Evidence From a Korean Population Study

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Ischemic stroke is influenced by long-term metabolic and renal deterioration, but many risk prediction frameworks rely on single time-point measurements.

Are multi-period patterns in metabolic screening indicators associated with incident ischemic stroke compared to single time-point assessments in a Korean population?

Population

194 908 individuals (97 454 matched pairs) from Korean National Health Insurance Service data

Comparison

Multi-period metabolic screening patterns vs single time-point indicators

Design

Propensity score-matched study using conditional logistic regression

Follow-up

2019-2023

Key result

Multi-period metabolic screening indicators, such as sustained fasting glucose ≥126 mg/dL (OR 1.66; 95% CI 1.60-1.73), were significantly associated with incident ischemic stroke.

Authors

IYInhyeok YimHJHeui Sug JoSKS C Kim

Discussion

Loading...

Member takes

Overview

Sustained BP and glucose elevations may raise stroke risk; leaves open whether multi-period monitoring improves prevention in practice.

Key Points

  • The aim is to determine the association between multi-period health screening indicators and incident ischemic stroke in Korea.
  • Analyzed National Health Insurance Service data with 3 biennial screenings (2013-2018)
  • Matched 97,454 pairs based on sex, age, and insurance type
  • Used conditional logistic regression to evaluate associations.
  • Increased waist circumference (OR 1.05, 95% CI 1.01 to 1.08) linked to stroke incidence.
  • Sustained blood pressure ≥130/80 mmHg associated with stroke (OR 1.34, 95% CI 1.31 to 1.37).
  • Sustained fasting glucose ≥126 mg/dL highly correlated with stroke (OR 1.66, 95% CI 1.60 to 1.73).

Study Design

Type

Cohort (n=194,908)

Multicenter

Yes

Structured PICO

Are multi-period patterns in metabolic screening indicators associated with incident ischemic stroke compared to single time-point assessments in a Korean population?

P
Population
194,908 individuals (97,454 matched pairs) from the Korean National Health Insurance Service with 3 biennial screenings (2013-2018), matched on sex, 1-year age strata, and insurance type.
I
Intervention
Multi-period assessment of metabolic screening indicators (waist circumference increase ≥10%, sustained blood pressure ≥130/80 mmHg, sustained fasting glucose ≥126 mg/dL, proteinuria progression, and creatinine elevation in ≥2 periods) over 3 biennial screenings.
C
Comparator
Single time-point assessment of metabolic screening indicators (P3-only model).
O
Outcome
Incident ischemic stroke during 2019-2023.hard clinical

Main Result

Effect estimate: OR 1.66 (95% CI 1.60-1.73)

Multi-year patterns in metabolic screening indicators are significantly associated with incident ischemic stroke, suggesting repeated measurements may improve risk prediction over single time-point assessments.

Cite This Study

Yim et al. (2026) conducted a cohort in Ischemic stroke (n=194,908). Multi-period metabolic screening indicators vs. Single time-point indicators was evaluated on Incident ischemic stroke (OR 1.66, 95% CI 1.60-1.73). Multi-period metabolic screening indicators, such as sustained fasting glucose ≥126 mg/dL (OR 1.66; 95% CI 1.60-1.73), were significantly associated with incident ischemic stroke.

synapsesocial.com/papers/6a1bd2515783ba022b6fdbachttps://doi.org/10.3961/jpmph.25.810
View Full Paper
Ask AI
Bookmark
Share