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June 1, 2026Frontiers in PediatricsOpen Access

Association between hematocrit and cranial MRI abnormalities in neonatal hyperbilirubinemia

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Authors

TLTing LiuLWLiang WangRJRufeng Ji

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Overview

Retrospective study finds higher hematocrit linked to increased cranial MRI abnormalities in neonates with hyperbilirubinemia, suggesting potential biomarker use.

Key Points

  • The aim is to clarify the relationship between hematocrit and cranial MRI abnormalities in neonates with hyperbilirubinemia.
  • Conducted a retrospective cross-sectional study of 410 neonates with hyperbilirubinemia.
  • Extracted neonatal blood parameters, maternal prenatal data, and cranial MRI findings from electronic medical records.
  • Employed logistic regression and smooth curve fitting for analysis.
  • Each 1% increase in hematocrit is associated with a 6% increase in the risk of cranial MRI abnormalities (OR not specified).
  • No significant interactions found with subgroup analyses based on sex, mode of delivery, or gestational diabetes (all P > 0.05).

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a1d20f302fbce9130637329https://doi.org/10.3389/fped.2026.1785949
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association between Hematocrit and Cranial MRI Abnormalities in Neonatal Hyperbilirubinemia2025
  2. 2Maternal Hematological Status in Third Trimester and Its Correlation With Neonatal Birth Weight2026
  3. 3Diagnostic prediction of neonatal hyperbilirubinemia combined with germinal matrix-intraventricular hemorrhage based on cranial ultrasound hemodynamics: a retrospective case-control study2025
  4. 4Association of High-Sensitivity Cardiac Troponin I, Platelet Counts, and Total Bilirubin/Albumin Ratio with the Severity of Neonatal Hyperbilirubinemia2025
  5. 5Hematocrit in the first 2 hours of life and short-term outcomes in very preterm infants: A secondary analysis from a prospective cohort study2025