Prospective observational study examines sedation effects on kidney markers in cats with chronic kidney disease, suggesting safety of the protocol.
Key Points
This research aims to evaluate the short-term impact of sedation on kidney function markers in cats suffering from chronic kidney disease (CKD).
Prospective observational study of client-owned cats with CKD undergoing abdominal sonography.
Sedation protocol included oral gabapentin, butorphanol, midazolam, and alfaxalone.
Blood tests for GFR markers were taken presedation and either at peak sedation or 2 hours post-sedation.
No significant difference in SDMA or creatinine concentrations was observed between presedation and peak sedation samples (P=0.31 for SDMA, P=0.71 for creatinine).
No significant change was noted between presedation and post-sedation samples taken after 2 hours (P=0.51 for SDMA, P=0.06 for creatinine).
Prolonged sedation was the only reported adverse effect.