Sarcopenia-associated CD8+ T-cell reconstitution predicts poor outcomes in severe aplastic anemia after hematopoietic stem cell transplantation | Synapse
June 1, 2026Open Access
Sarcopenia-associated CD8+ T-cell reconstitution predicts poor outcomes in severe aplastic anemia after hematopoietic stem cell transplantation
Key Points
To assess the relationship between sarcopenia-associated CD8+ T-cell reconstitution and clinical outcomes in severe aplastic anemia after hematopoietic stem cell transplantation.
Evaluated CD8+ T-cell levels in severe aplastic anemia patients post-HSCT
Assessed clinical outcomes based on T-cell reconstitution data
Lower CD8+ T-cell reconstitution correlated with adverse clinical outcomes
Observations suggest a predictive role of CD8+ T-cells in post-transplant prognosis
Abstract
T cells following HSCT in SAA patients, potentially improving posttransplant clinical outcomes.