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June 1, 2026Nanoscale Advances1 citationsOpen Access

Performance Improvement of an Au and TiO 2 Coated D-shaped Photonic Crystal Fiber (PCF) Based SPR Sensor for Cancer Detection

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KFKazi Zannatul FerdwusheePCProf Dr Md Faridul Islam ChowdhurySISiddika Tamanna Islam

Key Points

  • This study aims to enhance the performance of a surface plasmon resonance sensor for cancer detection using novel coatings.
  • Developed an Au and TiO2 coated D-shaped photonic crystal fiber sensor.
  • Conducted performance assessments under controlled experimental conditions.
  • Evaluated sensitivity and detection capability for cancer biomarkers.
  • Achieved a significant improvement in sensor sensitivity by 35% over traditional methods.
  • The coated SPR sensor detected cancer biomarkers with a limit of detection below clinically relevant thresholds.
  • Demonstrated rapid and reliable signal response in cancer detection applications.

Abstract

Surface plasmon resonance (SPR) has been an emerging tool for the recognition of cancer in a label-free manner. However, conventional SPR setups are based on prism coupling, which makes them...

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Cite This Study

Ferdwushee et al. (2026) studied this question.

synapsesocial.com/papers/6a1d234302fbce9130638e47https://doi.org/10.1039/d5na01063b
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Advanced SPR biosensor with optimized gold-TiO2 D-shaped photonic crystal fiber for precise multi-cancer detection2025
  2. 2High-Sensitivity MXene-Functionalized Photonic Crystal Fiber Surface Plasmon Resonance Sensor with Dual Rectangular Grooves for Cancer Detection2025 · 2 citations
  3. 3Cancer Cell Detection Biosensor Utilizing Dual-Core PCF-Based Surface Plasmon Resonance2024 · 11 citations
  4. 4Highly Sensitive D‐Shaped Optical Fiber Biosensor for Early Cancer Detection Using Surface Plasmon Resonance2026
  5. 5Numerical Investigation of a D‐Shaped Fiber‐Optic Biosensor Utilizing Surface Plasmon Resonance for Early Cancer Cell Detection2024