What does this research mean for the field?

In mixed granulocytic asthma, the OXPHOS pathway drives the metabolic reprogramming of Th17 cells to produce LIGHT, which controls airway remodeling, and dual blockade of LIGHT and OXPHOS reverses these disease features. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 22, 2026Open Access

The metabolic reprogramming of T cells controls airway remodeling in severe asthma

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Authors

HSHope Steele EKElizabeth Kato GDGarrison Dell

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Cite This Study

Steele et al. (2026) studied this question.

synapsesocial.com/papers/6a1d5b75266863fda62f2276 https://doi.org/10.64898/2026.03.19.712985

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March 22, 2026Open Access

The metabolic reprogramming of T cells controls airway remodeling in severe asthma

View Full Paper

Ask AI

Bookmark

Authors

HSHope Steele EKElizabeth Kato GDGarrison Dell

Discussion

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Steele et al. (2026) studied this question.

synapsesocial.com/papers/6a1d5b75266863fda62f2276 https://doi.org/10.64898/2026.03.19.712985

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