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June 2, 2026Troia Medical Journal0 citations

Association of CRP/albumin ratio with no-reflow in NSTEMI

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MÇMuhammet Cihat ÇelikMKMacit KalçıkADAbdullah Kadir Dolu

Key Result

Elevated high-sensitivity C-reactive protein/albumin ratio (CAR) was associated with angiographic no-reflow in NSTEMI patients undergoing PCI (median CAR 0.27 vs. 0.13).

Key Points

  • This study examined how well the CRP/albumin ratio predicts no-reflow in NSTEMI patients after PCI.
  • Retrospective evaluation of 400 NSTEMI patients treated with PCI from 2021 to 2023
  • Patients classified by post-procedural TIMI flow: no-reflow (TIMI ≤2) or normal reflow (TIMI 3)
  • Logistic regression and ROC analysis used to identify predictors and assess CAR's discriminative ability.
  • No-reflow occurred in 45 patients (11.3%).
  • No-reflow group exhibited higher hs-CRP and lower albumin, resulting in elevated CAR (median 0.27 vs. 0.13, p<0.05).

Study Design

Type

Observational (n=400)

Structured PICO

Does the high-sensitivity C-reactive protein/albumin ratio (CAR) predict angiographic no-reflow in NSTEMI patients undergoing PCI?

P
Population
400 NSTEMI patients treated with PCI between 2021 and 2023
I
Intervention
High-sensitivity C-reactive protein/albumin ratio (CAR) assessment
O
Outcome
Angiographic no-reflow (post-procedural TIMI flow ≤2)surrogate

Elevated high-sensitivity C-reactive protein/albumin ratio is associated with angiographic no-reflow in NSTEMI patients undergoing PCI.

Main Result

Absolute Event Rate: 0.27% vs 0.13%

Abstract

Objective: This study examined the predictive value of the high-sensitivity C-reactive protein/albumin ratio (CAR) for angiographic no-reflow in NSTEMI patients undergoing PCI.Methods: We retrospectively evaluated 400 NSTEMI patients treated with PCI between 2021 and 2023. Patients were classified by post-procedural TIMI flow: no-reflow (TIMI ≤2) or normal reflow (TIMI 3). Clinical, laboratory, and angiographic variables were compared. Logistic regression identified independent predictors, and ROC analysis assessed CAR’s discriminative ability.Results: No-reflow occurred in 45 patients (11.3%). Compared with normal reflow, the no-reflow group had higher hs-CRP, lower albumin, and thus elevated CAR (median 0.27 vs. 0.13, p

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Cite This Study

Çelik et al. (2026) conducted an observational in NSTEMI (n=400). High-sensitivity C-reactive protein/albumin ratio (CAR) was evaluated on Angiographic no-reflow (TIMI ≤2). Elevated high-sensitivity C-reactive protein/albumin ratio (CAR) was associated with angiographic no-reflow in NSTEMI patients undergoing PCI (median CAR 0.27 vs. 0.13).

synapsesocial.com/papers/6a1e72ad30b38c64201b5dc7https://doi.org/10.55665/troiamedj.1824706
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