The snATAC Atlas of Human Glioma

Key Points

• To create a comprehensive single-cell atlas that maps chromatin accessibility in human glioma tumors across multiple regions.
• Developed a multi-regional single-cell atlas using snATAC-seq technology.
• Analyzed chromatin accessibility profiles from human glioma samples.
• Characterized cellular heterogeneity and epigenetic landscapes within tumors.
• Identified distinct chromatin accessibility patterns associated with different tumor regions.
• Revealed cellular diversity and potential epigenetic regulators within glioma.
• Highlighted variations in tumor microenvironment across regions.