Forging Spiro-Dibenzoxazepane Indano-Succinimides through Direct Diastereoselective 3+2 Annulation

Key Points

• The aim is to develop a method for synthesizing spiro-dibenzoxazepane indano-succinimides through selective reactions.
• Utilized Cp*Rh(III) as a catalyst for the direct [3+2]-spiroannulation.
• Combined dibenz[b,f]oxazepines with N-substituted maleimides.
• Assessed broad substrate scope and functional-group tolerance.
• Successfully synthesized spiro-dibenzoxazepane indano-succinimides with high diastereoselectivity.
• Demonstrated excellent functional-group tolerance across various substrates.