Phytosterols from Lagenaria siceraria as novel bioactive compounds for the management of inflammatory and oxidative stress conditions: an in vitro and in silico approach

Key Points

• This research aims to investigate the potential of phytosterols from Lagenaria siceraria for managing inflammatory and oxidative stress conditions.
• In vitro assays to evaluate the effects of phytosterols on inflammation and oxidative stress.
• In silico analyses to predict the bioactivity of these compounds.
• Phytosterols significantly reduce markers of inflammation in vitro.
• Compounds demonstrate potential antioxidant activity, indicating effectiveness against oxidative stress.