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June 3, 2026JAMA Network OpenOpen Access

User-Directed vs Interruptive Real-Time Benefit Tools for Medication Changes in Primary Care

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Authors

RKRyan M. KaneTufts UniversitySMSarah Morton-OswaldDuke UniversityYLYuliya LokhnyginaDuke University

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Overview

Retrospective cohort study compares medication order changes linked to real-time benefit tool redesign in primary care, suggesting effective communication improves outcomes.

Key Points

  • To assess the impact of redesigning real-time benefit tools from user-directed to interruptive on medication order change frequencies and display rates.
  • Retrospective cohort study using electronic health record data from Duke Health between January 2022 and December 2023.
  • Participants included adults with multimorbidity prescribed at least one medication with display capability.
  • Generalized linear models were used to analyze changes in tool display frequency and medication order changes.
  • RTBT display frequency increased significantly from 1.3% in 2022 to 13.5% in 2023.
  • Interruptive design was associated with an increase in RTBT display frequency (RR, 9.62; 95% CI, 8.16-11.35) and in medication changes (RR, 8.37; 95% CI, 7.08-9.91).
  • No significant change in medication order changes per displayed RTBT was observed (RR, 0.93; 95% CI, 0.84-1.04).

Cite This Study

Kane et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc756dee9eb8c0dce8234https://doi.org/10.1001/jamanetworkopen.2026.15767
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