In doxorubicin-treated mice, exercise training blunted the increase in left ventricular glucose uptake, increased LV-weight and ejection fraction, and lowered LV lactate dehydrogenase activity.
Does exercise training ameliorate cardiac dysfunction in mice during doxorubicin treatment of breast cancer?
Exercise training may partly ameliorate doxorubicin-induced cardiac dysfunction and metabolic alterations in a mouse model of breast cancer.
Uurasmaa et al. (Mon,) conducted a other in Cardiac dysfunction during doxorubicin treatment of breast cancer. Exercise training vs. No exercise was evaluated on Cardiac function and metabolism (LV glucose uptake, LV-weight, ejection fraction). In doxorubicin-treated mice, exercise training blunted the increase in left ventricular glucose uptake, increased LV-weight and ejection fraction, and lowered LV lactate dehydrogenase activity.