Stress-induced down-regulation of CPEB4 disrupts sodium channel regulation and myocardial excitability, establishing the CPEB4-SCN5A axis as a therapeutic target in ischemic cardiomyopathy.
Absolute Event Rate: 0% vs 0%
5 and sodium current. The CPEB4-SCN5A axis is a key determinant of myocardial excitability under stress, and RNA stability may be targeted therapeutically to maintain electrical integrity in ischemic cardiomyopathy.
Kang et al. (Mon,) reported a other. Stress-induced down-regulation of CPEB4 disrupts sodium channel regulation and myocardial excitability, establishing the CPEB4-SCN5A axis as a therapeutic target in ischemic cardiomyopathy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: