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June 4, 20260 citationsOpen Access

Comparative Efficacy of Acellular Dermal Matrix with and without Injectable Platelet-Rich Fibrin, and Free Gingival Graft for Enhancement of Peri-Implant Keratinized Gingiva Width: A Randomized Controlled Clinical Trial

SSShahin ShahbazpeyMMMohammad MohammadiNLNazila Lashkarizadeh

Key Points

  • This research investigates the effectiveness of different periodontal interventions for increasing keratinized gingiva width around dental implants.
  • Randomized controlled clinical trial with 36 dental implants assigned to 3 groups (n=12 each)
  • Interventions included free gingival graft, acellular dermal matrix, and iPRF-impregnated ADM
  • Outcomes assessed included keratinized gingiva width, pain via visual analog scale, and graft shrinkage after 3 months.
  • Significant increase in keratinized gingiva width in all groups (P<0.001)
  • FGG resulted in greater keratinized gingiva width increase than both ADM and iPRF (P<0.001)
  • Postoperative pain was significantly lower in ADM/iPRF than FGG and ADM alone (P<0.001, P=0.002), with less pain in ADM than FGG (P=0.008).

Abstract

Background and Aim: This study compared the efficacy of acellular dermal matrix (ADM) with and without injectable platelet-rich fibrin (iPRF) and free gingival graft (FGG) for the enhancement of periimplant keratinized gingiva width (KGW).Materials and Methods: In this randomized controlled clinical trial, 36 dental implants with KGW0.05).Conclusion: All three tested methods significantly increased the periimplant KGW.Although FGG was the most effective for the enhancement of KGW, it was associated with the highest postoperative pain level.IPRF-impregnated ADM may be considered as an acceptable, less invasive, and less painful approach for patients not consenting to FGG, although it had no significant difference with ADM alone.

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Cite This Study

Shahbazpey et al. (2026) studied this question.

synapsesocial.com/papers/6a211549d499ed480b16e852https://doi.org/10.66224/jrdms.11.1.8
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