Glycoconjugated Re(CO) 3 + complexes: syntheses, characterization, cytotoxicity and cellular localization

Key Points

• This research aims to evaluate the synthesis and cytotoxic properties of glycoconjugated Re(CO)3+ complexes in cancer cells.
• Synthesized a stable, water-soluble glycoconjugated Re(CO)3+ complex.
• Investigated the cytotoxic effects on A2780 ovarian cancer cells.
• Examined cellular localization and uptake mechanisms mediated by glucose transport proteins.
• The glycoconjugated complex showed significant accumulation in nuclear/perinuclear regions of A2780 cells.
• Cytotoxicity was observed but specific metrics were not detailed in the abstract.