Indium(III)-catalysed regioselective N2-vinylation of tetrazoles with unactivated alkynes

Key Points

• The aim is to develop a method for N2-vinylation of tetrazoles using indium(III) as a catalyst.
• Utilized indium(III) as a dual role catalyst for vinylation.
• Explored regioselective reactions with unactivated alkynes.
• Employed cooperative Lewis acid activation strategies.
• Successful N2-vinylation of tetrazoles was achieved with varying alkynes.
• Regioselectivity was confirmed through reaction specificity with unactivated substrates.