Timing of Catheter Ablation for Ventricular Tachycardia in Ischemic Cardiomyopathy: Evidence, Mechanisms, and the Emerging Role of Timely ICD‐Guided Intervention
Why the study?
The optimal timing of catheter ablation for ventricular tachycardia in ischemic cardiomyopathy remains uncertain, with strategies ranging from prophylactic intervention to delayed treatment after recurrent arrhythmia.
Does the timing of catheter ablation (specifically ICD-guided intervention) improve arrhythmic and clinical outcomes in patients with ventricular tachycardia and ischemic cardiomyopathy?
Population
Patients with ventricular tachycardia in ischemic cardiomyopathy
Comparison
Different ablation timing strategies, including prophylactic, early, and ICD-guided approaches
Design
Structured narrative review
Key result
A timely ICD-guided approach to catheter ablation for ventricular tachycardia reduces VT recurrence and ICD therapies, with emerging signals of survival benefit.
Authors
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Supports ICD-guided ablation after first ICD therapy to reduce recurrences; leaves survival benefit open for randomized trials.
Does the timing of catheter ablation (specifically ICD-guided intervention) improve arrhythmic and clinical outcomes in patients with ventricular tachycardia and ischemic cardiomyopathy?
An ICD-guided approach to VT ablation, triggered by the first device-verified arrhythmic event, offers a biologically and clinically sound strategy to reduce VT recurrence and ICD therapies in ischemic cardiomyopathy.
Turreni et al. (2026) conducted a review in Ventricular tachycardia in ischemic cardiomyopathy. Timing of catheter ablation (prophylactic, early, and ICD-guided) was evaluated. A timely ICD-guided approach to catheter ablation for ventricular tachycardia reduces VT recurrence and ICD therapies, with emerging signals of survival benefit.