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June 4, 2026Journal of Agricultural and Food Chemistry0 citations

Novel Benzofuranone Insecticides Through Calix[4]arene-Based Strategy

From Rational Design to Bioactivity Enhancement: Novel Benzofuranone Insecticide Discovery Assisted by a Calix4arene-Based Supramolecular Strategy

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Authors

RZRenxuan ZouJZJinyang ZhouZYZiyan Yang

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Overview

Uncovers novel insecticidal candidates with low toxicity to bees, indicating potential for ecologically safe insecticides.

Key Points

  • The aim is to discover novel benzofuranone compounds that effectively serve as insecticides while minimizing bee toxicity.
  • Utilized a supramolecular strategy based on calix[4]arene to enhance bioactivity of benzofuranone compounds.
  • Evaluated the toxicity of the new compounds against bees.
  • C4A and C4A@5i demonstrated low toxicity levels to bees.
  • New benzofuranone compounds show promise as insecticidal candidates with safer ecological profiles.

Cite This Study

Zou et al. (2026) studied this question.

synapsesocial.com/papers/6a211611d499ed480b16f2b5https://doi.org/10.1021/acs.jafc.6c03260
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