Crystallographic and Theoretical Insights into a Fluorogenic Turn-On Probe for Selective Fe³⁺ Detection with Biomolecular Binding and In Vitro Anticancer Studies | Synapse
June 4, 2026Dalton Transactions0 citations
Crystallographic and Theoretical Insights into a Fluorogenic Turn-On Probe for Selective Fe³⁺ Detection with Biomolecular Binding and In Vitro Anticancer Studies
This research aims to develop a fluorogenic probe for selective detection of Fe³⁺ and evaluate its anticancer effects.
Utilized crystallographic techniques to characterize the probe's binding properties.
Performed in vitro anticancer studies to assess its therapeutic potential.
The fluorogenic probe showed high selectivity for Fe³⁺ with significant binding affinities.
In vitro experiments indicated enhanced anticancer activity at increasing concentrations.
Abstract
Ferric ions (Fe3+) play essential roles in oxygen transport and enzymatic processes, while their dysregulation is associated with disorders such as anaemia and cancer. In this study, we report the...