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June 4, 2026The Journal of Maternal-Fetal & Neonatal Medicine0 citationsOpen Access

Delivery-room escalation, risk factors, and early neonatal outcomes among term infants with a low 5-minute Apgar score in a regional Australian hospital: a case–control study

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SPSantosh PathakRTReji ThomasPDPrativa Dhakal

Key Points

  • The study aims to explore delivery-room interventions and risk factors linked to low 5-minute Apgar scores in term infants.
  • Examined 3,919 term births at a regional Australian hospital.
  • Conducted multivariable analysis of maternal and intrapartum factors associated with Apgar scores below 7.
  • Assessed delivery-room escalation and neonatal care requirements.
  • Incidence of Apgar <7 was 2.32%, higher than the national average of 1.4%.
  • 100% of cases required resuscitation compared to 41.8% of controls; code blue activation was 40.7% in cases vs 2.2% in controls.
  • Risk factors identified include cesarean delivery (aOR 2.60, 95% CI 1.21-5.58) and shoulder dystocia (aOR 9.38, 95% CI 1.07-82.54).

Abstract

BACKGROUND: Low 5-minute Apgar scores are widely used as indicators of neonatal compromise and in perinatal performance assessments, but interpretation varies by case mix and local escalation and transfer protocols, especially in regional (non-tertiary) hospitals. This study examines delivery-room escalation, early neonatal care, and maternal and intrapartum risk factors associated with Apgar scores below 7. METHODS: < 0.05. RESULTS: Among 3,919 term births, the incidence of a 5-minute Apgar score below 7 was 2.32%, higher than the national average (1.4%). Cases had higher odds of requiring active resuscitation, delivery room escalation, and higher-acuity postnatal care. Resuscitation was performed in 100% of cases versus 41.8% of controls; code blue activation occurred in 40.7% of cases and 2.2% of controls. Special Care Nursery admission was in 81.3% of cases; 6.6% required tertiary transfer, whereas controls were more often managed on the postnatal ward (50.5%). Multivariable analysis identified cesarean delivery (aOR 2.60, 95% CI 1.21-5.58), prolonged rupture of membranes (aOR 2.91, 95% CI 1.06-7.95), and shoulder dystocia (aOR 9.38, 95% CI 1.07-82.54) as associated with Apgar <7. Intrapartum morphine use (aOR 0.13, 95% CI 0.05-0.38) and previous cesarean (aOR 0.31, 95% CI 0.11-0.87) were inversely associated and potentially protective. CONCLUSION: In this regional, non-tertiary setting, a low 5-minute Apgar score, reported more frequently, identifies a clinically meaningful "at-risk transition" phenotype associated with a substantial, quantifiable escalation burden. Rather than being interpreted as an isolated quality figure, it may also inform more nuanced local audits, benchmarking, and service planning.

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Cite This Study

Pathak et al. (2026) studied this question.

synapsesocial.com/papers/6a2116fad499ed480b16fe12https://doi.org/10.1080/14767058.2026.2677979
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