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June 4, 2026JACC AsiaOpen Access

Frailty Is Not Futility

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Authors

MTMark TuttleUniversity of Colorado Health

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Overview

Randomized trial investigates the link between frailty and clinical outcomes, suggesting frailty does not imply futility.

Key Points

  • The aim is to explore the relationship between frailty and clinical outcomes, challenging the assumption that frail individuals have less favorable outcomes.
  • Conducted a randomized trial to assess clinical outcomes in frail individuals.
  • Evaluated the effect of specific interventions on frailty-associated outcomes.
  • The intervention improved clinical outcomes in frail patients, with significant improvement in certain biomarkers.
  • No evidence was found supporting the notion that frailty predicts futility in treatment outcomes.

Cite This Study

Mark Tuttle (2026) studied this question.

synapsesocial.com/papers/6a211a65d499ed480b170f9bhttps://doi.org/10.1016/j.jacasi.2026.03.026
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