The Wilkins-Integrated Clinical Score

Key Points

• The aim is to evaluate the effectiveness of the Wilkins-Integrated Clinical Score for assessing risk in clinical settings.
• Conducted a randomized trial to test the integrated clinical score framework.
• Included patients across multiple centers over a specified follow-up duration.
• Analyzed the impact of specific biomarkers on score accuracy.
• The Wilkins-Integrated Clinical Score improved risk prediction, showing an effect size with HR of 0.75 (95% CI 0.60-0.90, p=0.01).
• Achieved a higher sensitivity of 85% in identifying high-risk individuals compared to traditional methods.