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Cardiac contractility modulation (CCM) in heart failure patients with atrial fibrillation: A comprehensive review of the literature | Synapse
June 4, 2026
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Cardiac contractility modulation (CCM) in heart failure patients with atrial fibrillation: A comprehensive review of the literature
AA
Amro Assayed
University of Central Florida
HG
Hanan Gruhonjic
University of Central Florida
AM
Ashot Minasyan
University of Central Florida
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Key Points
This review aims to assess the impact of cardiac contractility modulation (CCM) on heart failure patients who also have atrial fibrillation.
Conducted a comprehensive literature review
Analyzed studies focusing on CCM interventions and outcomes in heart failure patients with atrial fibrillation
Evaluated the effectiveness of various therapeutic approaches
CCM shows potential to improve cardiac function in heart failure patients with atrial fibrillation.
Evidence indicates favorable outcomes regarding symptom relief and quality of life among treated patients.
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Assayed et al. (Mon,) studied this question.
synapsesocial.com/papers/6a211cc1d499ed480b170fd3
https://doi.org/https://doi.org/10.1016/j.ijci.2026.100006