An anionic cyanine probe with enhanced ROS-stability for butylcholinesterase detection in non-alcoholic fatty liver disease

Key Points

• The aim is to develop a probe for effective detection of butyrylcholinesterase in non-alcoholic fatty liver disease.
• Developed an ACy5-QL-BChE probe using an anionic cyanine dye.
• Targeted butyrylcholinesterase (BChE) for detection.
• Measured 762 nm emission with high signal-to-noise ratio.
• The ACy5-QL-BChE probe showed effective detection of BChE.
• High signal-to-noise ratio indicates improved sensitivity in measurements.