PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
October 28, 2003Circulation1,988 citationsOpen Access

Human Epicardial Adipose Tissue Is a Source of Inflammatory Mediators

View Full Paper
TMTomasz MazurekLZLifeng ZhangAZAndrew Zalewski

Structured PICO

P
Population
High-risk cardiac patients
O
Outcome
Presence of inflammatory mediators in epicardial adipose tissuesurrogate

Local inflammation in epicardial adipose tissue is not reflected by systemic biomarkers or eliminated by current therapies in high-risk cardiac patients.

Abstract

Epicardial adipose tissue is a source of several inflammatory mediators in high-risk cardiac patients. Plasma inflammatory biomarkers may not adequately reflect local tissue inflammation. Current therapies do not appear to eliminate local inflammatory signals in epicardial adipose tissue.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Mazurek et al. (2003) studied this question.

synapsesocial.com/papers/69d893b58c03fbaff8bef795https://doi.org/10.1161/01.cir.0000099542.57313.c5
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Preadipocyte Conversion to Macrophage2003 · 510 citations
  2. 2Plasma Concentration of Interleukin-6 and the Risk of Future Myocardial Infarction Among Apparently Healthy Men2000 · 2,447 citations
  3. 3Increased myocardial NADPH oxidase activity in human heart failure2003 · 578 citations
  4. 4Increased Myocardial Gene Expression of Tumor Necrosis Factor-α and Nitric Oxide Synthase-22002 · 69 citations
  5. 5Elevation of Tumor Necrosis Factor-α and Increased Risk of Recurrent Coronary Events After Myocardial Infarction2000 · 939 citations