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May 6, 2026Open Access

Combined Soft and Hard Tissue Facial Lesions In Early Childhood Pioneering the Diagnosis of the Tumor Predisposition Syndrome Neurofibromatosis Type 1.

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Authors

RFREINHARD E. FRIEDRICHFKFELIX K. KOHLRUSCHCHChristian Hagel

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Overview

Case report analyzes jaw and tooth development in a child with neurofibromatosis type 1, suggesting diagnostic potential for tumor-associated changes.

Key Points

  • The aim is to analyze the skeletal changes in the jaw and teeth associated with neurofibromatosis type 1.
  • Case report of a 2-year and 9-month-old male patient with a right-sided facial plexiform neurofibroma examined over 12.5 years.
  • Clinical and radiological evaluations were conducted to assess jaw dysmorphia and tooth development.
  • Long-term follow-up analyzed the interaction between the tumor and hard tissues.
  • Skeletal changes in the ramus and jaw angle progressed over time alongside tooth development.
  • Radiological findings indicated adaptive functions of tumor-coated bone preserving the condyle-fossa relationship.
  • Dental findings may offer insights into the timing of interactions between plexiform neurofibroma and hard tissues.

Cite This Study

FRIEDRICH et al. (2026) studied this question.

synapsesocial.com/papers/69fada7f03f892aec9b1e4abhttps://doi.org/10.21873/cdp.10552
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