Randomized trial examines sleep position and sex impacts on upper airway stimulation outcomes in obstructive sleep apnea, suggesting targeted therapeutic decisions.
Key Points
This study aims to determine how sleep position and sex affect upper airway stimulation therapy outcomes in obstructive sleep apnea.
Retrospective cohort analysis of patients implanted with hypoglossal nerve stimulation from January 2018 to June 2021.
Utilized sleep study scoring protocol to evaluate apnea-hypopnea index pre- and postoperatively.
Measured surgical response rates by sleep position (supine vs. lateral) and sex using Sher criteria.
In lateral sleep, HGNS success rate was 77.0%, and normalization of AHI was 54.1%; in supine sleep, 52.9% and 23.5%, respectively.
Females showed a greater supine AHI reduction and surgical response rate than males (p < 0.05).
Positional trends persisted regardless of the number of sleep studies conducted.