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March 25, 2026Alcohol Clinical and Experimental Research1 citations

Paternal lineage effects of prenatal ethanol exposure: Offspring neuroanatomy and behavior in a multigenerational mouse model of FASD

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KCKathleen E. ConnerRPRoberto F. PerezMEMichael A. Erickson

Key Points

  • This research investigates the effects of prenatal ethanol exposure on brain and behavior in mice across generations.
  • Used a multigenerational mouse model
  • Assessed neuroanatomy and behavior of offspring
  • Evaluated heritable effects of prenatal exposure
  • Identified abnormal brain development in offspring
  • Observed behavioral changes linked to prenatal ethanol exposure
  • Detected transgenerational heritable effects in subsequent generations

Abstract

Our data suggest that PrEE can result in abnormal brain and behavioral development with heritable effects that persist transgenerationally.

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Cite This Study

Conner et al. (2026) studied this question.

synapsesocial.com/papers/69c37be2b34aaaeb1a67ec79https://doi.org/10.1111/acer.70242
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