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April 10, 2026RSC Advances0 citationsOpen Access

Pico-molar determination of lurasidone hydrochloride in pharmaceutical formulations using PVC-membrane bulk Miptode

FAFatehy M. Abdel-HaleemYAYomna M. AhmedMEMenna M. El-Beshlawy

Key Points

  • This research aims to accurately measure very low concentrations of lurasidone hydrochloride using a specialized detection method.
  • Used a molecularly imprinted polymer to enhance sensitivity.
  • Developed a PVC-membrane bulk optode for optical detection.
  • Focused on detecting picomolar concentrations of the drug.
  • Successfully detected lurasidone hydrochloride at pico-molar levels.
  • Demonstrated the effectiveness of the modified optode in pharmaceutical formulations.

Abstract

The optical detection of picomolar levels of lurasidone hydrochloride using a molecularly imprinted polymer modified bulk optode.

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Cite This Study

Abdel-Haleem et al. (2026) studied this question.

synapsesocial.com/papers/69d893a86c1944d70ce0495ehttps://doi.org/10.1039/d5ra07784b
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