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April 10, 2026Current Cancer Drug Targets0 citations

NDUFA10: An Emerging Oncogenic Driver of Metastasis in LungAdenocarcinoma

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THTao HuYCYun ChenYLYue Lu

Key Points

  • This research aims to investigate the role of NDUFA10 in the progression of lung adenocarcinoma (LUAD).
  • Experimental silencing of NDUFA10 in LUAD cells
  • Assessment of cell proliferation, migration, and invasion
  • Evaluation of the regulatory effects of circRAPGEF5 on NDUFA10
  • NDUFA10 silencing significantly suppresses LUAD cell proliferation
  • Migration and invasion of LUAD cells are inhibited upon NDUFA10 silencing
  • CircRAPGEF5 is identified as a regulator of NDUFA10, impacting LUAD progression

Abstract

Silencing NDUFA10 suppresses LUAD cell proliferation, migration, and invasion. The study suggested that circRAPGEF5 regulated NDUFA10 to facilitate the progression of LUAD.

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Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/69d893eb6c1944d70ce04f10https://doi.org/10.2174/0115680096440556260123113410
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