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April 10, 2026Journal of Cosmetic Dermatology0 citationsOpen Access

Hydroquinone‐Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health

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MMMcKenzie E. MaloneyMHMay Mabel HallRKRyan C. Kelm

Key Points

  • This research focuses on evaluating the effects of THD-AA serum on skin health, specifically concerning hyperpigmentation and aging.
  • Clinical assessments of skin health post-application of THD-AA serum
  • Molecular analysis of reactive oxygen species (ROS) buffering
  • Monitoring changes in melanogenesis levels
  • THD-AA serum significantly buffered reactive oxygen species (ROS)
  • Notable reduction in melanogenesis was observed
  • Antiaging effects were observed, suggesting overall improved skin health

Abstract

THD-AA serum has clinical and molecular efficacy in buffering ROS, reducing melanogenesis, and promoting antiaging, providing a safe alternative to hydroquinone products.

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Cite This Study

Maloney et al. (2026) studied this question.

synapsesocial.com/papers/69d895a86c1944d70ce06aefhttps://doi.org/10.1111/jocd.70826
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Also Consider

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  5. 5A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties2006 · 84 citations