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April 10, 2026PLoS ONE0 citationsOpen Access

Text encryption through bio-inspired DNA and RNA sequencing

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OROmar Fitian RashidSASafa Ahmed AbdulsahibHAHumam Al-Shahwani

Key Points

  • This research aims to develop a novel encryption method based on biological mechanisms to enhance information security.
  • Introduced a six-step encryption system using DNA and RNA sequences.
  • Encoded plaintext into DNA sequences and transcribed them into RNA.
  • Applied complementary base pairing and scrambled RNA segments.
  • Included optional reverse transcription before encoding to ciphertext.
  • Tested the efficiency of this method with varying message sizes.
  • Demonstrated high efficiency in encryption and decryption time.
  • Each encryption instance showed significant randomness due to the biological approach.
  • Created new opportunities for secure cryptographic systems inspired by biological processes.

Abstract

Cryptography is the technology of protecting information and communication by means of encoding the sending information. Existing methods often operate within predetermined mathematical structures which can be subject to pattern recognition and which are lack biological randomness. To address these challenges, this paper introduced a new bio-inspired cryptography approach to protect text messages using the coding mechanisms of DNA and RNA materials. The encryption system consists of six steps: encoding the plaintext message into DNA sequences, transcribing DNA into RNA, applying the complementary base pairing, scrambling RNA segments, optional reverse transcription, and encoding the resulting DNA-RNA characters into ciphertext. Randomization is used in the encoding of DNA and in the scrambling of RNA to make each encryption instance different from the other. This method was tested with varying sizes of messages, and it has proved very efficient in terms of time between encryption and decryption. This approach has created new opportunities for the creation of new classes of secure cryptographic systems bio-inspired to get modern methods of digital communication.

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Cite This Study

Rashid et al. (2026) studied this question.

synapsesocial.com/papers/69d896166c1944d70ce075b8https://doi.org/10.1371/journal.pone.0345090
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