This scientific statement provides a broad overview of nonvascular physical and psychologic variables affecting brain health across the life span to provide a framework for future studies.
Brain health and cognitive resilience
脑健康的概念（即脑在认知、情感和行为领域的最佳功能状态）及认知弹性（即脑在受损后恢复的能力）随着人口老龄化愈加重要。既往研究关注脑血管疾病的血管危险因素，以及促使早老化和认知功能障碍的可调变量。在本科学声明中，我们重点关注影响全生命周期脑健康的非血管性身体和心理变量。我们广泛综述了影响发育中大脑的慢性疾病、炎症、环境暴露及社会经济因素，以及影响神经退行性变的睡眠质量、肠道微生物组和心理健康等因素。我们还回顾了支持生物学机制和缓解策略证据的强度，旨在为未来研究提供框架。
“We've long focused on managing risk factors like blood pressure and cholesterol, which remain critical for heart and brain health, however, this statement spotlights research on external factors like sleep quality, the gut microbiome and social conditions that are also associated with brain health.”
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Elisabeth B. Marsh
Helen Lavretsky
Nadine A. Kasparian
Stroke
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Marsh 等人（周二）进行了脑健康与认知弹性的综述。该科学声明广泛回顾了影响全生命周期脑健康的非血管性身体和心理变量，为未来研究提供框架。
www.synapsesocial.com/papers/69f221911dbee6adbbcdd015 — DOI: https://doi.org/10.1161/str.0000000000000518
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