Cardiac resynchronization improved symptoms, quality of life, and reduced death risk in heart failure patients, complementing standard pharmacologic therapy.
Does cardiac resynchronization reduce the composite of death or unplanned hospitalization for a major cardiovascular event in patients with NYHA class III/IV heart failure, left ventricular systolic dysfunction, and cardiac dyssynchrony?
Patients with New York Heart Association class III or IV heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony who were receiving standard pharmacologic therapy
Cardiac resynchronization added to standard medical therapy
Standard medical therapy alone
Composite of time to death from any cause or an unplanned hospitalization for a major cardiovascular eventcomposite
In patients with moderate or severe heart failure and cardiac dyssynchrony, adding cardiac resynchronization to standard pharmacologic therapy significantly reduces the risk of death and major cardiovascular hospitalizations.
In patients with heart failure and cardiac dyssynchrony, cardiac resynchronization improves symptoms and the quality of life and reduces complications and the risk of death. These benefits are in addition to those afforded by standard pharmacologic therapy. The implantation of a cardiac-resynchronization device should routinely be considered in such patients.
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John G.F. Cleland
Jean‐Claude Daubert
Erland Erdmann
New England Journal of Medicine
University of Birmingham
Istituti di Ricovero e Cura a Carattere Scientifico
University of Cologne
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Cleland et al. (Mon,) reported a other. Cardiac resynchronization improved symptoms, quality of life, and reduced death risk in heart failure patients, complementing standard pharmacologic therapy.
www.synapsesocial.com/papers/6967d6e9e36b71fd5d83145a — DOI: https://doi.org/10.1056/nejmoa050496
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