Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates.

Key Points

• To evaluate the susceptibility of various clinical gram-negative bacterial isolates to minocycline.
• Collection of clinical gram-negative bacterial isolates
• Testing minocycline efficacy in vitro
• Comparison with susceptibility patterns of ceftriaxone and other antibiotics
• Minocycline demonstrated activity against multidrug-resistant E. coli
• Effective against ceftriaxone-resistant K. pneumoniae isolates
• Showed in vitro efficacy against non-fermenting bacteria like Acinetobacter and Stenotrophomonas

Abstract