ABSTRACT 3‐(2‐formylcycloalkenyl)‐acrylic ester (FCAE) acts as an important building block in synthetic organic chemistry. Co‐existence of α, β‐unsaturated ester and α, β‐unsaturated aldehyde makes it a useful scaffold for the synthesis of diverse carbocyclic and heterocyclic compounds through Michael addition, condensation reaction, coupling reaction, multicomponent reaction, cascade cyclization, functional group conversion, and asymmetric synthesis. The literature covers the area since last couple of decades. In this review, we outline the various pathways for bicyclic, tricyclic, tetracyclic, pentacyclic, and polycyclic heterocyclic scaffolds with their mechanistic details.
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Sampa Mondal
Biswajit Ghosh
Rabindra Nath Sana
ChemistrySelect
Jadavpur University
Saha Institute of Nuclear Physics
KIIT University
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Mondal et al. (Sun,) studied this question.
www.synapsesocial.com/papers/699010df2ccff479cfe571fd — DOI: https://doi.org/10.1002/slct.202505976
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