Synthesis of MONO- and BIS-Polyfluoroalcholate Derivatives Containing Aryl Ethers and Thioethers

A series of p-substituted tetrafluoroaldehydes and ketones were obtained by the interaction of pentafluoroacetophenone and pentafluorobenzaldehyde with an excess of 4,4-thiobisthiophenol, 4,4-thiobisphenol and tert-butylthiophenol. The use of a twofold excess of pentafluoroacetophenone and pentafluorobenzaldehyde in the reaction with respect to 4,4-thiobisthiophenol and 4,4-thiobisphenol leads to the formation of bis-octafluoroaldehydes and ketones in high yields. New mono- and bis-polyfluoroalcoholanes containing aryl ethers and thioethers and capable of further modifications were synthesized on the basis of mono- and bis-substituted aldehydes and ketones.