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March 1, 2026Open Access

A plasma metabolomic fingerprint of moderate or severe hearing loss

Puntos clave

The research aims to explore the relationship between plasma metabolomic profiles and the risk of adult-onset moderate or severe hearing loss.
Conducted a population-based investigation
Analyzed plasma metabolomic profiles
Identified associations between metabolites and hearing loss
Triglycerides showed positive associations with hearing loss
Steroid esters exhibited inverse associations with hearing loss
Metabolic perturbations may contribute to the development of hearing loss

Resumen

In this population-based investigation, we identified that triglycerides were enriched for positive associations, while steroid esters were inversely associated with adult-onset moderate or severe hearing loss. This study indicates that metabolic perturbations may contribute to the pathoetiology underlying adult-onset hearing loss.

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Authors

Y

Y. Li

C

Catherine Schairer

D

D. Bradley Welling

Journals

Metabolomics

Actions

Institutions

Harvard University

Stanford University

Brigham and Women's Hospital

References and Citations

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Cite this study

Li et al. (Fri,) studied this question.

www.synapsesocial.com/papers/69a3d8caec16d51705d2ffee — DOI: https://doi.org/10.1007/s11306-026-02395-8

A plasma metabolomic fingerprint of moderate or severe hearing loss | Synapse