Enhancement slope of ultrafast dynamic contrast-enhanced MRI: a promising biomarker for assessing Crohn’s disease activity

Key Points

• The enhancement slope significantly correlates with Crohn's disease activity, indicating its potential use as a biomarker.
• First, enhancement slope metrics showed a strong relationship with clinical scores of disease severity in 100 participants.
• Observational analysis using ultrafast dynamic contrast-enhanced MRI measured the enhancement slope of 100 patients with Crohn’s disease.
• Findings support the enhancement slope as a promising, non-invasive biomarker for evaluating Crohn’s disease activity.