March 3, 2026

Idiopathic generalised epilepsies in 2026

Key Points

Valproate remains the most effective treatment for idiopathic generalized epilepsies despite its teratogenic effects.
Women planning pregnancy face challenges due to valproate's risks, which require careful management.
Psychiatric comorbidities are common in idiopathic generalized epilepsies, necessitating comprehensive treatment approaches.
Holistic care can address both seizure control and mental health, improving overall life quality.

Abstract

Valproate continues to be the most efficacious treatment for IGE but also the most teratogenic, leaving women who plan to become pregnant in a dilemma. Psychiatric comorbidities are frequent in IGE and thus require special attention and a holistic treatment approach.

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Discussion

Authors

Eva Breuer

Bernd J. Vorderwülbecke

Martin Holtkamp

Journals

Current Opinion in Neurology

Actions

Institutions

Charité - Universitätsmedizin Berlin

Humboldt-Universität zu Berlin

Freie Universität Berlin

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Idiopathic generalised epilepsies in 2026

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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