March 3, 2026Open Access

Prognostic value of ctDNA-derived maximum somatic allele frequency in patients with metastatic gastric cancer

Key Points

Baseline maximum somatic allele frequency correlates with outcomes in metastatic gastric cancer.
A notable increase in maximum somatic allele frequency was linked to worse prognostic implications with survival.
Assessment of baseline maximum somatic allele frequency serves as a method for enhanced risk stratification in clinical practice.
Incorporating this biomarker may improve personalized treatment approaches, yet external validation is necessary.

Abstract

Baseline MSAF is an independent prognostic biomarker in metastatic GC and may reflect underlying biological aggressiveness. Incorporating MSAF into risk stratification frameworks could enhance prognostic classification and inform personalized treatment strategies.

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Authors

Changgon Kim

Young-Gon Kim

Jihwan Moon

Journals

Therapeutic Advances in Medical Oncology

Actions

Institutions

Sungkyunkwan University

Samsung Medical Center

Korea University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Prognostic value of ctDNA-derived maximum somatic allele frequency in patients with metastatic gastric cancer

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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