The glymphatic system clears amyloid beta and tau from brain to plasma in humans

Key Points

• Interstitial fluid clearance involves both amyloid beta and tau, indicating a dual role in eliminating neurotoxic proteins.
• Amyloid beta and tau levels significantly decreased in plasma, demonstrating effective transfer from the brain.
• Analysis across human subjects showed that the glymphatic system plays a crucial role in brain health and disease prevention.
• This finding highlights the importance of the glymphatic system in understanding and treating neurodegenerative diseases.