Lactate-lactylation in tumor angiogenesis and progression: mechanisms, biomarker potential, and therapeutic implications

Key Points

• Tumor angiogenesis is significantly influenced by lactate-lactylation mechanisms, impacting progression.
• The study identifies specific biomarkers linked to lactate-lactylation involvement in angiogenesis.
• Observational analysis highlights potential therapeutic implications of targeting lactate-lactylation pathways.
• Understanding these mechanisms may enable innovative treatment strategies and improve patient outcomes.