TDCIPP disrupts decidual macrophage function to induce miscarriage through ferroptosis-mediated DNA damage

Key Points

• Miscarriage is induced by TDCIPP-mediated disruption of decidual macrophage function, leading to ferroptosis.
• Key evidence indicates that DNA damage associated with ferroptosis is significantly elevated after TDCIPP exposure.
• Analysis of macrophage function demonstrates how TDCIPP disrupts normal physiological processes in the decidua and induces miscarriage.
• Highlights the potential environmental impact of TDCIPP exposure on reproductive health and necessitates further investigation.